Search Results for metipranolol

Nevertheless, metipranolol like other beta-receptor blocking agents, e.g. timolol or bupranolol, should not be administered to patients with asthma bronchiale (Demmler, N., Müller-Bardorff, G., 1980 [5]; Demmler, N., 1980 [6]).

Author: H.-J. Merte

Publisher: Springer Science & Business Media

ISBN: 9783709140673

Category: Medical

Page: 171

View: 976

After a compound and its various effects - or, as the case may be, any particular one of these - have been discovered there is still a long way ahead until it is available for use in daily practice as a finished product. Before reaching the doctor, the substance is examined by chemists, pharmacologists and pharmacists - just to mention a few of the most important stages in a whole research sequence. Before the drug is finally made available on the market, the findings resulting from animal experiments must be confirmed in clinical studies. The expectations involved in its development must be met, and sufficient evidence has to be established as to the drug's effects and side effects, indications and contraindications, and the questions of safe use and appropriate dosage. Only then may the drug be registered and introduced to the market. In this respect Metipranolol eye drops, which have recently been launched on the market, formed no exception and had likewise to go through all these various stages. A series of investigators at many different centers participated in this procedure, and at the invitation of the manufacturers, Messrs. Dr. Gerhard Mann, they assembled for discussions at a symposium held in Berlin in January 1983, and reported on the substance and their experiences with it.
2013-06-29 By H.-J. Merte

Other studies have shown that compared with a placebo,all β-blockers result in some degree of systemic beta-blockade, and the increasing order of potency is betaxolol (0.5%),metipranolol (0.6%),and timolol (0.5%).

Author: Jimmy D. Bartlett

Publisher: Elsevier Health Sciences

ISBN: 9780750675765

Category: Medical

Page: 793

View: 668

This text provides more than theoretical information on pharmacological mechanisms by focusing on the practical uses of drugs in the primary care of patients. It aims to enable students and clinicians to stay informed of developments.

tested with metipranolol eye drops and there were 13 (15%) positive reactions. The patients were not tested with the active substance, but reactions to the (possible) adjuvants benzalkonium chloride, sodium EDTA and sodium disulfite ...

Author: Anton C. de Groot

Publisher: CRC Press

ISBN: 9781000367911

Category: Medical

Page: 874

View: 421

This third volume in an exciting and detailed series on contact allergens provides monographs of all 384 topical drugs which have caused contact allergy/allergic contact dermatitis. The monographs present: Identification section; Contact allergy (general population, patients with dermatitis, case reports and case series); Cross-reactions; Patch test sensitization; Photocontact allergy; and Immediate contact reactions (contact urticaria). Separate chapters present an overview of all aspects of allergic contact dermatitis to topical drugs, contact allergy to non-drug ingredients in topical pharmaceuticals and a preview of delayed-type allergy to systemic drugs (to be discussed in Volume 4). Key Features: Presents monographs of all known topical drugs which have caused contact allergy/allergic contact dermatitis Provides a full literature review of relevant topics of allergenic topical drugs Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents non-drug allergens in topical pharmaceuticals Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy
2021-02-16 By Anton C. de Groot

1% pindolol eyedrops with the result that metipranolol caused marked impairment of bronchopulmonary function, while pindolol caused no change in airway resistance and forced expiratory volume (Bleckmann 1986).

Author: W. Morton Grant

Publisher: Charles C Thomas Publisher

ISBN: 9780398082154

Category: Electronic books

Page: 1626

View: 300

The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.
1993-01-01 By W. Morton Grant

with metipranolol 0.3% for more than 6 months [60]. In a large retrospective cohort study on 1928 patients treated with 0.3 % metipranolol and 3,903 patients using other beta-blockers for glaucoma, Beck et al. did not find any case of ...

Author: Manfred Zierhut

Publisher: Springer

ISBN: 9783540753872

Category: Medical

Page: 1609

View: 752

This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
2016-01-12 By Manfred Zierhut

[ 72 ] Metipranolol - Pilocarpine A fixed combination of pilocarpine 2 % and metipranolol 0.1 % was reported to have a ... of four fixed - dose metipranolol and pilocarpine combinations in ocular hypertension and glaucoma patients .

Author: Steve M. Reece

Publisher: Nova Publishers

ISBN: 1594541280

Category: Medical

Page: 303

View: 692

Glaucoma is a group of disorders characterised by an abnormally high intraocular pressure (IOP), which can damage the optic nerve and lead to blindness. Glaucoma occurs in several forms: chronic open-angle (primary), acute angle-closure, congenital (inherited as an autosomal recessive trait), and secondary to other causes. Chronic open-ended glaucoma constitutes about 90% of the instances of glaucoma and is frequently familial in nature. Congenital glaucoma can be triggered by varicella, mumps, parvovirus, HIV and herpes among others. Secondary glaucoma can result from trauma and drugs such as steroids. This new book includes within its scope the prevention, pathogenesis, etiology, diagnosis and treatment of glaucoma. International research efforts are reported.
2005 By Steve M. Reece

Dies steht im Gegensatz zu einer altersunabhängigen lokalanästhetischen Wirkung für Propranolol und Bupranolol (Buhr-Unger et al. 1980). Bei der Applikation von 1%igem Metipranolol tritt der Effekt ebenfalls unmittelbar ein.

Author: G. K. Krieglstein

Publisher: Springer-Verlag

ISBN: 9783642805028

Category: Medical

Page: 252

View: 458

2013-03-12 By G. K. Krieglstein

20,32 Metlipranolol-Butlizid composition Metipranolol-Butlizid Combined 3-blocking, 3.3 -Dihydralazin diuretic and vasodilatating effect for hypertension treatment Metipranolol-Butlizid Combined treatment of 34 dihydralazin-C Methyl ...


Publisher: Academic Press

ISBN: 0080861148

Category: Science

Page: 665

View: 726

Profiles of Drug Substances, Excipients and Related Methodology
1991-01-28 By

Watanabe and Hodes (1997) reported a case with bilateral granulomatous uveitis due to metipranolol (without argon treatment). Beck et al (1996) found no cases of uveitis in retrospective studies of 1928 patients on 0.3% metipranolol or ...

Author: Frederick T. Fraunfelder

Publisher: Elsevier Health Sciences

ISBN: 9781437719673

Category: Medical

Page: 384

View: 277

Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and its current Director, this essential resource provides the clinically relevant information you need to effectively diagnose and manage herbal, chemical, and drug-related ocular problems. Comprehensive coverage of all drugs’ generic and trade drug names, primary uses, ocular and systemic side effects, and clinical significance make this book - like its best-selling predecessor, Drug-Induced Ocular Side Effects - the ideal reference for quick, on-the-spot consultation. Leaders in the field provide need-to-know information on all aspects of ocular toxicology—all in one concise reference. Data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden) help you recognize and avoid drug-induced ocular side effects. A highly templated format makes retrieval of essential knowledge quick and easy. A wealth of full-color photographs provide vivid, visual diagnostic guidance. The latest information on approved medications helps you stay up to date and provide state-of-the-art care. Extensive coverage of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics gives you the knowledge you need to manage any challenge in ocular toxicology Authoritative guidance on ocular drugs and their use in pregnancy helps you safely manage the unique needs of these patients. The inclusion of the WHO classification system helps you determine whether a particular side effect is certain, probable, or likely to occur.
2008-06-12 By Frederick T. Fraunfelder

ARTERIAL THROMBOSIS VENOUS THROMBOSIS 26 ° C + Dipyridamole 3 mg / kg p.o. leg 4 . mg T + Metipranolol 1 mg / kg p.o. T + 27 3 7 2 28 1 29 T1 1 0 1 2 3 4 Metipranolol mg / kg p.o. 6 T0 0.3 1 3 Dipyridamole mg / kg p.o. FIGURE 30.

Author: Josef Hladovec

Publisher: CRC Press

ISBN: 9781000098556

Category: Medical


View: 215

Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. The methods form an integrated system stressing particularly the plurifactorial and global character of thrombosis and the key role of a generalized mild endothelial lesion. Packed with illustrations, this book documents the effectiveness of the system through the screening of a series of acknowledged and potential antithrombotics, and includes a unique study of their mutual combinations. Special emphasis is placed on the importance of biomodels for preliminary testing of antithrombotics. This book is particularly useful to researchers in pharmacology and the pharmaceutical industry; however, those interested in drug research and the field of cardiovascular medicine will benefit as well.
2020-11-26 By Josef Hladovec